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The Truth About Long-Term Melatonin Use: Are You at Risk for Heart Issues?

Update Melatonin Use: A Double-Edged Sword for Sleep As executives and entrepreneurs navigate the demands of their high-pressure lives, sleep often takes a back seat to productivity. Yet, a recent study raises pivotal questions about the long-term use of melatonin supplements—widely touted for their potential to promote better sleep and combat insomnia. While melatonin is often perceived as a safe, natural remedy, emerging research suggests that prolonged consumption could carry significant health risks, particularly concerning cardiovascular health. Understanding the New Findings on Melatonin A study unveiled at the American Heart Association's Scientific Sessions in November 2025 explored the health records of over 130,000 adults with chronic insomnia. The results were startling: those who used melatonin for over a year faced a staggering 90% higher risk of developing heart failure compared to non-users (4.6% vs. 2.7%). Furthermore, melatonin users were nearly 3.5 times more likely to require hospitalization for heart failure (19.0% vs. 6.6%). Melatonin: What You Need to Know Melatonin is a hormone produced naturally by the body that plays a key role in regulating sleep-wake cycles. Although often available over-the-counter as a dietary supplement, it's crucial to know that these products are not regulated by the FDA, which can lead to discrepancies between the labeled and actual content. A study found that over 70% of melatonin supplements tested contained doses that varied significantly from what was stated on the label, leading to potential unintended effects. Caution: The Case Against Long-Term Use Many people turn to melatonin to alleviate sleep struggles, especially during times of high stress. However, experts are urging caution regarding long-term usage. The findings that link melatonin with heart disease provide a valid reason for concern, suggesting that those relying on it for extended periods may have underlying health issues that require different treatment approaches. Melatonin Across Generations: Rising Use and New Guidelines With increasing reports of melatonin use among both adults and children, health officials have begun to emphasize the necessity for medical guidance. The American Academy of Sleep Medicine issued advisories in response to the uptick in cases, particularly among children experiencing melatonin overdoses. It is emphasized that adults should engage healthcare professionals to explore alternative sleep strategies rather than relying solely on melatonin. Beyond Melatonin: Alternative Solutions for Sleep For those grappling with chronic insomnia—affecting about 10% of adults—there are numerous strategies to enhance sleep quality without resorting to medication. Cognitive Behavioral Therapy (CBT) is a well-supported treatment option that helps address sleep-related thoughts and behaviors effectively. Additionally, practical lifestyle changes can go a long way, including maintaining a consistent sleep schedule, creating a conducive sleeping environment, reducing screen time before bed, and avoiding stimulants and heavy meals in the evening. Final Thoughts: Navigating Sleep Health Safely This emerging research shifts our understanding of melatonin from a seemingly harmless sleep aid to a compound warranting caution. As we prioritize productivity in our busy lives, ensuring quality sleep is essential—not just for immediate performance, but for long-term heart health and overall wellness. If you experience persistent insomnia, consider seeking professional help to explore effective, evidence-based treatments tailored to your needs. Seek guidance from a healthcare provider to assess your sleep strategy and cardiovascular health today.